Description
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium sulfate, or DSS-induced apoptosis and caspase-3 activity. Besides, is a potential anti-neoplastic target in bladder cancer progression and inflammatory arthritis.
This Human UNC5B overexpression lysate was created in HEK293 Cells and intented for use as a Western blot (WB) positive control. Purification of UNC5B protein from the overexpression lysate was verified